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KMID : 0882420130840050704
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Korean Journal of Medicine
2013 Volume.84 No. 5 p.704 ~ p.707
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Colonic Langerhans Cell Histiocytosis Presenting as an Isolated Polyp
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Seo Hyun-Woong
Han Koon-Hee
Kim Sung-Hun
Hong Man-Yong
Yun Jung-Ho
Eom Dae-Woon
Cheon Gab-Jin
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Abstract
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A 56-year-old male underwent a screening colonoscopy. An 8-mm sessile polyp was removed from the descending colon using snare polypectomy. Histology showed Langerhans cells and eosinophil infiltration of the submucosa. Immunohistochemical staining was positive for S-100 protein and CD1a antigen, which confirmed the diagnosis of Langerhans-cell histiocytosis. On further workup, there was no evidence of involvement of any other organs. Here, we report a very rare case of colonic Langerhans-cell histiocytosis presenting as an isolated polyp.
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KEYWORD
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Langerhans-cell histiocytosis, Colon, Polyps, S-100 protein, CD1a antigen
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